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Carfentanil is 100 times more potent than Fentanyl, meaning it is 10,000 times more potent than morphine. This drug is not approved for use in humans in any capacity, and it is typically found in veterinary medicine to sedate large animals, primarily elephants.
In fact, the drug is so powerful that when veterinarians handle Carfentanil, they use protective gear so they don’t breathe it in or absorb it through their skin.
Carfentanil’s powder potency, the effects on the human body and brain are very rapide move onto increasingly potent and dangerous synthetic opioids such as carfentanyl.. Even in elephants, the sedative effects are especially rapide.
According to Elephant Care International, veterinarians must watch elephants for signs of pulmonary edema and capillary bleeding, characterized by a pink foam issuing from the elephant’s trunk, which indicates a potentially fatal rise in blood pressure.
.While doses administered to elephants are specifically to knock the animal unconscious, the doses are small compared to doses of much less powerful narcotics, like Oxycodone or hydrocodone, given to humans to treat pain. When even a fraction of the dose given to elephants is administered to humans, onset is rapide, difficult to stop, and hard to treat.
Carfentanil powder rapidly binds to opioid receptors in the brain, overwhelming neutral chemistry and leading to overdose symptoms almost immediately.
Fentanyl, for comparison, creates an intense euphoria and drowsiness when binding to the opioid receptors in the brain.
These sensations are caused by elevated dopamine levels and a reduced ability for the opioid receptors to absorb this neurotransmitter due to the presence of the narcotic. These receptors also control breathing rate, which is why opioid overdoses are typically characterized by depressed, irregular, or stopped breathing.
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